TY - JOUR AU - Chakraborty, Amrita AU - Ankita, AU - Nisha Kumari , AU - Ratnesh Kumar, PY - 2023/03/14 Y2 - 2024/03/29 TI - Synthesis of azepinoindolone derivative using Larock’s heteroannulation as key step JF - RESEARCH REVIEW International Journal of Multidisciplinary JA - rrijm VL - 8 IS - 3 SE - Articles DO - 10.31305/rrijm.2023.v08.n03.008 UR - https://rrjournals.com/index.php/rrijm/article/view/517 SP - 52-64 AB - <p><img src="https://rrjournals.com/public/site/images/admin/abstract.png" alt="" width="330" height="205"></p><p>Synthesis of tetrahydroazepino[4,5-b] indol-2(1H)-one derivative was achieved via intramolecular lactamization of the corresponding amine prepared from suitably designed 2,3-disubstituted indole. Larock’s heteroannulation was employed to get 2,3-disubstituted indole from tosyl protected 2-iodoaniline and internal alkyne which was prepared according to the methodology reported by Greg Fu.&nbsp;&nbsp;</p> ER -